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A statistical framework for case-control analysis of H&E whole slide images

Tanya Roysam [1,2,4,5], Yakir Reshef MD, PhD [1,2,4,5], Soumya Raychaudhuri MD, PhD [1,2,3,4,5]

1 Center for Data Sciences, Brigham and Women’s Hospital, Boston, MA, USA, 2 Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA, 3 Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA, 4 Broad Institute of MIT and Harvard, Cambridge, MA, USA, 5 Division of Genetics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA